Breakthrough cancer research technologies to advance treatments

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With support from the Australian Cancer Research Foundation, the Walter and Eliza Hall Institute has today unveiled the $2.5 million ACRF Breakthrough Technologies Laboratory which will help researchers uncover new insights into how cancer develops, and how it can be more effectively treated.

This is the third ACRF grant awarded to Walter & Eliza Hall Institute of Medical Research. These grants were awarded 2001, 2010 and 2014 with a combined value of $5.5 million to help researchers make breakthroughs in genomics, as well as breast, lymphoma and lung cancers.

The ACRF Breakthrough Technologies Laboratory is Australia’s first dedicated cancer laboratory to use ‘CRISPR/Cas9’ technology to target and directly manipulate genes in cancer cells.

The facility will be used by researchers from WEHI and the Victorian Comprehensive Cancer Centre (VCCC) partners to enhance and accelerate research into many of Australia’s most common, and most deadly, cancers including cancers of the blood (leukaemia, lymphoma), breast, ovary, lung and bowel.

The director of the WEHI, Professor Doug Hilton, said the ACRF Breakthrough Technologies Laboratory would provide an enormous boost to Australia’s cancer research efforts. “It has become clear that technologies such as CRISPR/Cas9 can accelerate new breakthroughs in understanding cancer and developing new treatments.”

“The generosity of ACRF and its donors has allowed us to equip our research teams with precisely the tools they need to advance their research,” Professor Hilton said.

Mr Tom Dery, Chairman of the ACRF Board said “We are proud to enable the ground-breaking research conducted at the ACRF Breakthrough Technologies Laboratory. The facility will help to accelerate new treatments for people with cancer in Australia and worldwide.”

The contributions Australian researchers are making to improve the prevention, diagnosis and treatment of cancer are very significant. “More than 14 million people around the world were diagnosed with cancer last year, including more than 125,000 Australians,” Mr Dery said.

Professor Jim Bishop, Executive Director of the VCCC, said the ACRF Breakthrough Technologies Laboratory represented a critical addition to the Victoria’s cancer research capabilities. “The facility provides our researchers with unparalleled access to world-leading technology.”

“The strength of the VCCC lies in the close ties it fosters between the laboratory-based, clinical and other researchers in its partner organisations. This means that discoveries made in the ACRF Breakthrough Technologies Laboratory will be translated into new treatments for cancer as rapidly in Melbourne as anywhere in the world,” Professor Bishop said.

The VCCC is an alliance of ten successful Victorian organisations committed to cancer care: the Walter and Eliza Hall Institute of Medical Research, Peter MacCallum Cancer Centre, Melbourne Health (including The Royal Melbourne Hospital), The University of Melbourne, The Royal Women’s Hospital, The Royal Children’s Hospital, Western Health, St Vincent’s Hospital Melbourne Austin Health and Murdoch Children’s Research Institute.

The original article was published on the Walter and Eliza Hall Institute website, click here to view.

Congratulations to ACRF medical research advisor, Professor Doug Hilton

Director of the Walter and Eliza Hall Institute of Medical Research, Professor Douglas Hilton has been awarded the Milstein Award in Florence, Italy.

The Milstein Award is considered to be the pinnacle of scientific achievement in interferon and cytokine research, which involves the study of the immune system and cell communication.

We congratulate Professor Hilton on this most prestigious award and thank him for his contributions to cancer research. Continue reading “Congratulations to ACRF medical research advisor, Professor Doug Hilton”

Blood stem cells discovery to boost cancer research progress

A study partially funded by the Australian Cancer Research Foundation (ACRF) creates opportunities in the way some cancer patients can be treated. The blood stem cell discovery has been made by scientists from the Walter and Eliza Hall Institute (WEHI) in Melbourne.

Led by Professor Doug Hilton, Dr Samir Taoudi and their research teams, the scientists discovered that the Erg gene is key to blood stem cells’ unique ability to self-renew. Research in blood stem cells allows scientists to develop new strategies to combat disease of the blood cells, like leukaemia. Continue reading “Blood stem cells discovery to boost cancer research progress”

ACRF awards $8.5 million to 4 world-class cancer research initiatives

Australia’s best scientists have been given a major boost in their fight against cancer, with the announcement of $8.5 million worth of grants from the ACRF to the nation’s finest research institutions.

The Foundation awarded a total of three grants – to $2million grant to The Walter and Eliza Hall Institute (Melbourne), $2.4million to Western Australian Institute for Medical Research and $1.6million to Monash Institute of Medical Research (Melbourne).  This is in addition to the ‘top-up’ grant of $2.5 million the ACRF pledged earlier to The Kinghorn Cancer Centre, a joint facility of the Garvan Institute of Medical Research and St. Vincent’s Hospital in Sydney.

Continue reading “ACRF awards $8.5 million to 4 world-class cancer research initiatives”