Research Institute: Children's Cancer Institute of Australia
Amount granted: $3.1 million
Year granted: 2007
ACRF funds were awarded to create an integrated and dedicated Drug Discovery Centre for Childhood Cancer, focusing specifically on defined molecular targets for improved treatment of childhood cancer.
The project aimed to identify and validate bona fide molecular targets in various forms of childhood cancer. ACRF funding provided all necessary scientific equipment and instrumentation to fully fit-out the ACRF Drug Discovery Centre for Childhood Cancer.
Researchers have used a combined approach aimed at first defining novel targets in specific pathways required by the cancer cell, and, second, using this information to design and test large-scale, small molecule screening strategies in a drug discovery process.
This $3.1 million grant offered by the ACRF has been made possible through a generous bequest by the Estate of the late Mrs Berenice M McDonnell.
Chief Investigators: Prof Michelle Haber, Prof Phil Hogg, Prof Murray Norris, Prof Glenn Marshall, Prof Maria Kavallaris, Prof Levon Khachigian, Prof Andrei Gudkov
What your donations have achieved
Cervical cancer vaccine
We gave initial seed funding to Professor Ian Frazer’s research into the cervical cancer (HPV). Over 150 million doses of vaccine have been delivered worldwide to date.
The pill that melts away cancer
Our long term support of cancer research at WEHI has led to a treatment that melts away certain advanced forms of chronic lymphocytic leukaemia. It has been approved for clinical use in the US, European Union and Australia and is being trialled for other types of cancer.
Personalised cancer diagnosis
In 2015, we awarded $10 million seed funding to an ambitious cancer proteome project that aims to provide each cancer patient a personalised treatment plan within 36 hours. This will improve treatment outcomes and help avoid unnecessary treatments.
Zero childhood cancer
We are one of the founding partners of the initiative that will tackle the most serious cases of infant, childhood and adolescent cancer in Australia. It is a key step towards the program vision of one day helping to cure 100% of children with cancer.