Olivia Newton-John Cancer Research Institute
The $2 million ACRF grant will fund a state-of-the-art imaging centre to understand how and why tumours corrupt the normal cells of their immediate environment.
The grant enables the Olivia Newton-John Cancer Research Institute (ONJCRI) and La Trobe Institute of Molecular Science (LIMS) to extend its ground-breaking work on the interaction between individual tumour cells and normal cells, and accelerate the speed with which results in the laboratory can be translated into treatments for cancer patients.
“Cellular interactions are crucial for tumours – they drive the growth of tumours and their spread to metastatic sites; these interactions are also often responsible for tumours becoming resistant to targeted therapy,” Professor Matthias Ernst, Scientific Director of ONJCRI, said.
“This new centre will literally shine a light on what happens in the micro-environment around a tumour, giving us the information we need to develop effective, targeted anti-cancer therapies.”
“We know that tumour cells coerce and corrupt their environment to their advantage. If we understand the interactions and mechanisms they use to do this, we will better understand how to counter them.”
What your donations have achieved
Cervical cancer vaccine
We gave initial seed funding to Professor Ian Frazer’s research into the cervical cancer (HPV). Over 150 million doses of vaccine have been delivered worldwide to date.
The pill that melts away cancer
Our long term support of cancer research at WEHI has led to a treatment that melts away certain advanced forms of chronic lymphocytic leukaemia. It has been approved for clinical use in the US, European Union and Australia and is being trialed for other types of cancer.
Personalised cancer diagnosis
In 2015, we awarded $10 million seed funding to an ambitious cancer proteome project that aims to provide each cancer patient a personalised treatment plan within 36 hours. This will improve treatment outcomes and help avoid unnecessary treatments.
Zero childhood cancer
We are one of the founding partners of the initiative that will tackle the most serious cases of infant, childhood and adolescent cancer in Australia. It is a key step towards the program vision of one day helping to cure 100% of children with cancer.