ACRF Centre for Imaging the Tumour Environment

  • Research Institute: Olivia Newton-John Cancer Research Institute

  • Amount granted: $2 million

  • Year granted: 2017

The $2 million ACRF grant will fund a state-of-the-art imaging centre to understand how and why tumours corrupt the normal cells of their immediate environment.

The grant enables the Olivia Newton-John Cancer Research Institute (ONJCRI) and Latrobe Institute of Molecular Science (LIMS) to extend its ground-breaking work on the interaction between individual tumour cells and normal cells, and accelerate the speed with which results in the laboratory can be translated into treatments for cancer patients.

“Cellular interactions are crucial for tumours – they drive the growth of tumours and their spread to metastatic sites; these interactions are also often responsible for tumours becoming resistant to targeted therapy,” Professor Matthias Ernst, Scientific Director of ONJCRI, said.

“This new centre will literally shine a light on what happens in the micro-environment around a tumour, giving us the information we need to develop effective, targeted anti-cancer therapies.”

“We know that tumour cells coerce and corrupt their environment to their advantage. If we understand the interactions and mechanisms they use to do this, we will better understand how to counter them.”

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