ACRF Centre for Intravital Imaging of Niches for Cancer Immune Therapy

  • Research Institute: Garvan Institute of Medical Research

  • Amount granted: $3.0 million

  • Year granted: 2020

$3M has been awarded to establish the ACRF Centre for Intravital Imaging of Niches for Cancer Immune Therapy at Sydney’s Garvan Institute of Medical Research.  

This world-first Australian-designed custom intravital microscopy centre at Garvan Institute will overcome the limitations of conventional microscopes in viewing the interactions between the immune system and cancer, below the surface of tumours and deep inside tissues. This work will address a major challenge in the treatment of cancer: why some patients have a remarkable clinical response to cancer immunotherapies, while other patients do not respond.  

“The ACRF INCITe Centre will overcome the technical challenges of imaging the molecular details of how the immune system interacts with cancer in vivo. By looking in the ‘dark spaces’ deep inside tumours, we hope to finally answer clinically important questions that we have not been able to answer before. We aim to reveal crucial insights that will allow us to develop new therapeutic approaches for eradicating cancer cells in all patients,” says Chief Investigator Prof Tri Phan from the Garvan Institute of Medical Research. 

Support for personnel to be involved in ACRF Intravital Imaging of Niches for Cancer Immune Therapy Centre has been provided by Cancer Institute NSW ($300,000 over 3 years), continuing the valued collaboration.  

The Cancer Institute NSW is delighted to partner with the Australian Cancer Research Foundation in supporting a role with the skills to optimise the use of this machine. By supporting this new investment, new knowledge will be developed that will help to accelerate cancer control. says Professor David Currow, Chief Cancer Officer NSW and CEO CI NSW

Other ACRF grants awarded to Garvan Institute of Medical Research