ACRF Centre for Cancer Epigenetics
The research program sought out to identify genes involved in maintaining the genome in the ‘correct’ epigenetic state. ACRF’s funding provided fit-out of equipment for the centre.
Epigenetics is the study of mechanisms which modify DNA structure, and thus change gene expression, without influencing the DNA base sequence. This program had a particular interest in the molecular mechanisms of epigenetic modification and how these mechanisms influence phenotype.
Such information has relevance to our ability to understand the genesis and development of cancer both for familial and sporadic cancer. In 2007, this was a new area of research.
This research program at QIMR was the first of its kind in the world and used the power of forward genetics to identify new genes involved in a range of human cancers.
Chief Investigators: Professor Emma Whitelaw, Professor Georgia Chenevix-Trench, Professor Nick Hayward
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