ACRF Drug Discovery Centre for Childhood Cancer

ACRF funds were awarded to create an integrated and dedicated Drug Discovery Centre for Childhood Cancer, focusing specifically on defined molecular targets for improved treatment of childhood cancer. The project aimed to identify and validate bona fide molecular targets in various forms of childhood cancer. ACRF funding provided all necessary scientific equipment and instrumentation to fully fit-out the ACRF Drug Discovery Centre for Childhood Cancer. Researchers have used a combined approach aimed at first defining novel targets in specific pathways required by the cancer cell, and, second, using this information to design and test large-scale, small molecule screening strategies in a drug discovery process. This $3.1 million grant offered by the ACRF has been made possible through a generous bequest by the Estate of the late Mrs Berenice M McDonnell. Chief Investigators: Prof Michelle Haber, Prof Phil Hogg, Prof Murray Norris, Prof Glenn Marshall, Prof Maria Kavallaris, Prof Levon Khachigian, Prof Andrei Gudkov